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小分子PEG
DM4PEG m-PEG16-alcoho Pyrene-PEG3-azide N3-PEG9-COOH HO-PEG16-OH N3-PEG4-COOH N3-PEG5-NH2 Ms-PEG3-Ms PEG13 m-PEG10-alcohol mPEG7-COOH m-PEG3-alcohol Tr-PEG9 THP-PEG4 Acid-PEG6-SS-PEG6-acid H2N-PEG8-COOH 2-(t-Butoxycarbonylamido)-1 Dibenzocyclooctyne-acid HO-PEG10-tBu DM1 THP-PEG9 m-PEG8-alcohol m-PEG8-Ms 2-(Biotin-amido) N3-PEG6-CH2CH2COOtBu Mal Tr-PEG3 Fmoc m-PEG9-CH2COOH THP-PEG6 m-PEG7-CH2COOH Propargyl-PEG7-alcohol N3-PEG5-SPA, N3-PEG1-CH2CO2H PEG21 N-Boc-Tris Acid-PEG3-SS-PEG3-acid N3-PEG2-COOH DBCO-S-S-PEG3-biotin m-PEG3-Ms m-PEG6-CH2COOH THP-PEG7 Sulfo-NHS-Acetate Mal-C4-NH-Boc Azido-SS-PEG2-acid N3-PEG10-NHS Tr-PEG6 1,3-bis(carboxyethoxy)-2,2-bis( N3-PEG9-NH2 PEG16 Tr-PEG7 N3-PEG12-COOH m-PEG13-Ms Tos-PEG6-Tos MC-MMAF SPDP m-PEG9-alcohol PEG15 Tetrazine-Acid N3-PEG10-COOH SPDP-C6-NHS ester t-Boc-Cystamine N3-PEG5-OH PEG8-Tos N3-PEG8-OH Ms-PEG8-Ms MC-Val-Cit-PAB-OH N3-PEG36-COOH Acid-PEG2-SS-PEG2-acid Ald-PEG4-azide Sulfo-NHS Auristatin E, THP-PEG12 N3-PEG6-NH2 N3-PEG8-NH2 m-PEG5-CH2COOH m-PEG4-alcohol m-PEG6-Ms PEG12 m-PEG2-COOH PROPARYL-PEG3-ME m-PEG4-CH2COOH N3-PEG8-NHS N3-PEG7-OH N3-PEG4-CH2CH2COOtBu THP-PEG3 PEG5-Ms Azide-SS-biotin Fmoc-PEG4-Ala-Ala-Asn-PAB m-PEG11-alcohol N3-PEG5-CH2CH2COOtBu N3-PEG1-NH2 2-t-Butoxycarbonylamino-1 Tr-PEG4 Fmoc-Val-Cit-PAB-OH, Thiol PEG Tetrazine-PEG TCO-PEG Sugar PEG Propargyl PEG Poly PEG PEG-X-PEG PEG Tosylate PEG Sulfonic acid PEG Phosphonate PEG PFP ester PEG Peptide PEG NHS ester PEG Maleimide PEG azide PEG Aldehyde PEG Acid Non-PEG linker MeNH-PEG m-PEG Hydroxy(OH) PEG Fluorescent PEG DSPE PEG DNP-PEG DBCO PEG Cleavable PEG Bromo PEG Boc-PEG Biotin PEG Benzyl-PEG Aminooxy PEG Amino PEG Alkyne PEG
磷脂
熒光染料
螯合劑
點擊試劑
高分子PEG
交聯劑
抑制劑
有機硅
雜環砌塊
金屬催化劑
多肽
分析試劑
Biotin

雙功能蛋白交聯劑和生物素交聯劑介紹的結構式和功能介紹

時間:2019/6/14閱讀:2185
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雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)

 

蛋白質交聯劑是一類小分子化合物,具有2個或者更多的針對特殊基團(-NH2、-COOH、-HS等)的反應性末端,可以和2個或者更多的分子分別偶聯,從而使這些分子結合在一起,終形成共軛蛋白。

Protein crosslinkers are chemical compounds used to covalently bind, or conjugate, biomolecules together. In proteomics, "protein crosslinking" refers to utilizing protein crosslinkers to conjugate peptides or proteins together or to immobilize proteins to a solid support.

Protein crosslinking reagents possess reactive moieties specific to various functional groups (sulfhydryls, amines, carbohydrates, etc.) on proteins, peptides, or other molecular complexes. The atoms separating a crosslinker’s reactive groups, and eventually the conjugated proteins, form the “spacer arm”. A zero-length crosslinker refers to protein crosslinkers that join two molecules without adding additional spacer arm atoms. Homobifunctional crosslinkers have the same reactive group on both ends of the spacer arm (i.e., Amine Reactive-Amine Reactive); while heterobifunctional crosslinkers have different reactive groups on each end of a spacer arm (i.e., Sulfhydryl Reactive-Amine Reactive).

 

西安凱新生物科技有限公司可以提供一系列的蛋白交聯劑,包含有同端雙功能交聯劑,異端雙功能交聯劑,氘代交聯劑,生物素交聯劑及其他種類交聯劑等等產品。我們提供的交聯劑產品小包裝是100毫克,價格便宜,品質較好深受廣大科研客戶歡迎。

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Zero-Length Crosslinkers零長度交聯劑:

產品名稱:Sulfo-NHS

產品簡介:N-hydroxysulfosuccinimide (Sulfo-NHS) is used in conjunction with EDC-HCl (EDAC-HCl) to convert carboxyl groups to Sulfo-NHS esters which react amines. Sulfo-NHS is used as a catalyst for EDC-HCl coupling and greatly increases the efficiency of the reaction.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
分子量: 217.1

CAS #: 106627-54-7

Alternative Name: Hydroxy-2,5-dioxoyrrolidine-3-sulfonate

 

Homobifunctional Crosslinkers 同端雙功能交聯劑:

產品名稱:BS3

產品介紹:BS3 crosslinker (Bis[sulfosuccinimidyl] suberate; BS3) is a water soluble homobifunctional pro-tein crosslinker. The 8-atom spacer arm of the BS3 crosslinking reagent is non-cleavable and the molecule is not cell membrane permeable. The BS3 protein crosslinker possesses amino reactive Sulfo-NHS esters on both ends of the molecule and can be used to prepare antibody-protein con-jugates or for crosslinking cell surface proteins.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

分子量:572 Da

CAS #: 82436-77-9

Spacer Length: 11.4 Å

Alternative Names: Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester); BS3; Sulfo-DSS

 

產品名稱:BS2G

簡介:BS2G crosslinker (Bis[Sulfosuccinimidyl] glutarate) is a water soluble homobifunctional protein crosslinker. The BS2G protein crosslinker's 5-atom (7.7 angstrom) spacer arm is non-cleavable and the molecule is not cell membrane permeable. The BS2G crosslinking reagent's Sulfo-NHS esters are amino reactive and can be used to label cell surface proteins.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 530.4

Spacer Length: 7.7 Å

Alternative Names: Glutaric acid bis (3-sulfo-N-hydroxysuccinimide ester); Sulfo-DSG

 

產品名稱:BSG

簡介:DSG crosslinker (Disuccinimidyl glutarate) is a homobifunctional crosslinking reagent that is membrane permeable. DSG crosslinking takes place through amine-reactive NHS esters at both ends of a 5-atom (7.7 angstrom) spacer arm. DSG must be dissolved in an organic solvent, such as DMSO or DMF, then added to an aqueous crosslinking reaction.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 326.3

CAS #: 79642-50-5

Spacer Length: 7.7 Å

Alternative Name: Di(N-succinimidyl) glutarate

 

產品名稱:DSP

簡介:Dithiobis(succinimidyl propionate) (DSP) is a homobifunctional crosslinker that is cell membrane permeable. DSP has amine-reactive N-hydroxysuccimide (NHS) esters at both ends of a cleava-ble, 8-atom (12.0 angstrom) spacer arm. DSP contains a reducible disulfide bond in the spacer arm that make it a good choice for various applications.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 404.4

CAS #: 57757-57-0

Spacer Length: 12.0 Å

Alternative Names: 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester);

 

產品名稱:DSS

簡介:DSS crosslinker (Disuccinimidyl suberate) is a homobifunctional crosslinker that is cell membrane permeable. DSS has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm. The DSS crosslinking reagent must be dissolved in an or-ganic solvent, such as DMSO or DMF, then added to an aqueous crosslinking reaction.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 368.4

CAS #: 68528-80-3

Spacer Length: 11.4 Å

Alternative Name: Suberic acid bis(N-hydroxysuccinimide)

 

產品名稱:DTSSP

簡介:DTSSP crosslinker (3,3´-Dithiobis[sulfosuccinimidylpropionate]) is a homobifunctional protein crosslinker that is cell membrane impermeable. DTSSP crosslinking reagent has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm. DTSSP contains a reducible disulfide (thiol) bond in the spacer arm that make it a good choice for various applications.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 608.5

CAS #: 81069-02-5

Spacer Length: 12.0 Å

 

產品名稱:EGS

簡介:EGS crosslinker, Ethylene glycolbis(succinimidylsuccinate), is a water insoluble homobifunction-al crosslinker. The 12-atom spacer arm of the EGS crosslinking reagent is cleavable. The EGS spacer arm is cleaved by hydroxylamine at pH 8.5 for 3-6 hours at 37°C. The EGS protein cross-linker possesses amino reactive NHS esters on both ends of the molecule and can be used to label intracellular proteins, since the molecule is cell membrane permeable.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 456.36

CAS #: 70539-42-3

Spacer Length: 16.1 Å

 

產品名稱:Sulfo-EGS

簡介:Sulfo-EGS crosslinker, Ethylene glycolbis(sulfosuccinimidylsuccinate), is a water soluble homo-bifunctional crosslinker. The 12-atom spacer arm of Sulfo-EGS crosslinking reagent is cleavable. Sulfo-EGS spacer arm is cleaved by hydroxylamine at pH 8.5 for 3-6 hours at 37°C. The Sulfo-EGS protein crosslinker possesses amino reactive Sulfo-NHS esters on both ends of the molecule and can be used to label cell surface proteins, since the molecule is not cell membrane permeable.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 660.45

Spacer Length: 16.1 Å

Alternative Names: Ethylene glycol bis (sulfosuccinimidylsuccinate);

 

產品名稱:DSSeb

簡介:DSSeb (Disuccinimidyl sebacateis membrane permeable. DSSeb crosslinks via amine-reactive NHS esters at both ends of a 10-atom (14.1 Å ) spacer arm and must dissolved in an organic sol-vent, such as DMSO or DMF, then added to an aqueous crosslinking reaction.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 396.39

CAS # 23024-29-5

Spacer Length: 14.1 Å

Alternative Names: Sebacic acid bis(N-hydroxysuccinimide ester);

 

Heterobifunctional Crosslinkers異端雙功能交聯劑:

產品名稱:BMPS

簡介:BMPS is a non-cleavable, water insoluble, heterobifunctional protein crosslinker that is common-ly used to crosslink haptens to carrier proteins and enzymes to antibody. The BMPS crosslinker's spacer arm length of 5.9 angstroms is the shortest of the C3 homolog of aliphatic spacer series (see also EMCS and GMBS). The BMPS crosslinking reagent's NHS ester and maleimide reac-tive groups react with amino and sulfhydryl moites, respectively.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 266.2

CAS #: 55750-62-4

Spacer Length: 5.9 Å

Alternative Names: N-(beta-Maleimidopropyloxy)succinimide ester

 

產品名稱:EMCS

簡介:N-(e-Maleimidocaproyloxy)succinimide ester (EMCS) is a non-cleavable, water insoluble, hetero-bifunctional crosslinker that is commonly used to crosslink haptens to carrier proteins and en-zyme to antibody. The EMCS crosslinker spacer arm is longer than GMBS. The EMCS NHS es-ter and maleimide reactive groups react with amino and sulfhydryl moieties, respectively.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 308.3

CAS #: 55750-63-5

Spacer Length: 9.4 Å

Alternative Names: N-(epsilon-Malaimidocaproyloxy) succinimide

 

產品名稱:GMBS

簡介:GMBS is a non-cleavable heterobifunctional protein crosslinker. The GMBS crosslinking reagent is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The GMBS has a spacer arm length of 7.3 angstroms and is less immunogenic than the crosslinking analog MBS. The GMBS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 280.2

CAS #: 80307-12-6

Spacer Length: 7.3 Å

Alternative Name: 4-Maleimdobutyric acid N-succinimidyl ester

 

產品名稱:LC-SPDP

簡介:LC-SPDP crosslinker is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive het-erobifunctional protein crosslinker. The "long chain" LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, compared to the 6.8 angstrom spacer arm of SPDP.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 425.5

Spacer Length: 15.7 Å

Alternative Name: Succinimidyl-6-(3-[2-pyridyldithiol-propionamido) hexanoate

 

產品名稱:MBS

簡介:MBS crosslinker is a non-cleavable, water insoluble, heterobifunctional protein crosslinking rea-gent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The MBS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 314.3

CAS #: 58626-38-3

Spacer Length: 7.3 Å

 

產品名稱:PDPH

簡介:PDPH is a cleavable, heterobifunctional protein crosslinking reagent. The PDPH crosslinker's hydrazide group selectively reacts with oxidized carbohydrates (or carboxyls when used with EDC); while the pyridinyldisulfide moiety is reactive toward reduced thiols. Thus, PDPH protein crosslinker is an excellent choice for crosslinking glycoproteins and other polysaccharides.

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 229.3

Spacer Length: 9.2 Å

Alternative Name: 3-[2-Pyridyldithio]propionyl hydrazide

 

產品名稱:SBA

簡介:SBA crosslinker (N-Succinimidyl bromoacetate) is a sulfhydryl (thiol) and amino reactive hetero-bifunctional protein crosslinking reagent. SBA crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents known with a spacer arm length of only 1.5 Angstroms.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 236.02

CAS #: 42014-51-7

Spacer Length: 1.5 Å

Alternative Names: Bromoacetic acid N-hydroxysuccinimide ester;

 

產品名稱:SIA

簡介:N-Succinimidyl iodoacetate (SIA) is a non-cleavable, heterobifunctional protein crosslinker. SIA is among the shortest amine and sulfhydryl (thiol) reactive crosslinkers known with a spacer arm length of 1.5 Angstroms.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 283.02

CAS #: 39028-27-8

Spacer Length: 1.5 Å

Alternative Names: Iodoacetic acid N-hydroxysuccinimide ester; Succinimidyl iodoacetate

 

產品名稱:SMCC

簡介:SMCC crosslinker (Succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate) is a heterobi-functional protein crosslinker with a maleimide group that is sulfhydryl (thiol; -SH) reactive and a NHS ester group that is amine reactive. The SMCC crosslinking reagent is permeable across the lipid bilayer of the cell membrane. The 9 atom spacer arm of SMCC is not cleavable.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 334.3

CAS #: 64987-85-5

Spacer Length: 8.3 Å

Alternative Names: 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester;

 

產品名稱:SMPB

簡介:SMPB crosslinker (N-Succinimidyl 4-[4-maleimidophenyl]butyrate) is a heterobifunctional pro-tein crosslinking reagent that is reactive toward sulfhydryl and amino groups. The SMPB pro-tein crosslinker is an extended chain length analog of MBS crosslinker.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 356.3

CAS #: 79886-55-8

Spacer Length: 11.6 Å

Alternative Name: 4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester

 

產品名稱:SMPH

簡介:SMPH crosslinker (Succinimidyl-6-[ß-maleimidopropionamido]hexanoate) is a water insoluble, heterobifunctional protein crosslinker with a non-cleavable spacer arm length of 14.3 angstroms. The SMPH crosslinking reagent has maleimide groups which are reactive to thiols (sufhydryls) and its NHS ester groups react with amines at pH 6.5-7.5 and 7-9, respectively

結構式:

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 379.4

Alternative Name: Succinimidyl-6-[βmaleimidopropionamido] hexanoate

 

產品名稱:SPDP

簡介:SPDP crosslinker is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobi-functional protein crosslinker. The SPDP crosslinking reagent's reactive moites consist of an N-hydroxysuccinimide (NHS) ester that reacts with primary amines. On the other end of SPDP, the pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 312.4

CAS #: 68181-17-9

Spacer Length: 6.8 Å

Alternative Name: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester

 

產品名稱:Sulfo-LC-SPDP

簡介:Sulfo-LC-SPDP crosslinking reagent is a cleavable, water soluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker.

Sulfo-LC-SPDP crosslinker's reactive moites consist of an N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines. The other end of the Sulfo-LC-SPDP crosslinking molecule pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 527.6

Spacer Length: 15.7 Å

Alternative Name: Sulfosuccinimidyl-6-(3’-[2-pyridyldithio]-propionamido) hexanoate

 

產品名稱:Sulfo-MBS

簡介:Sulfo-MBS crosslinker (m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester) is a non-cleavable, water soluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carri-er proteins and enzymes to antibody. The Sulfo-MBS crosslinking reagent's NHS ester and maleimide reac-tive groups react with amine and sulfhydryl moites, respectively.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 416.3

Spacer Length: 7.3 Å

Alternative Names: 3-Maleimidobenzoic acid N-hydroxysulfosuccinimide ester;

 

產品名稱:Sulfo-SANPAH

簡介:Sulfo-SANPAH crosslinker (N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate) is a water soluble, heterobifunctional protein crosslinker with a spacer arm length of 18.2 Å. Sul-fo-SANPAH crosslinking reagent contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 492.4

CAS #: 102568-43-4

Spacer Length: 18.2 Å

 

產品名稱:Sulfo-SMCC

Sulfo-SMCC crosslinker (Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate) is a water soluble, heterobifunctional crosslinker. Sulfo-SMCC crosslinking reagent has an 8.3 angstrom non-cleavable spacer arm and its maleimide group reacts with sulfhydryls (thiols), while the Sulfo-NHS ester is reactive toward primary amines. Sulfo-SMCC can be used to pro-duce antibody-protein crosslinked conjugates or efficiently label cell surface proteins.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 436.4

CAS #: 92921-24-9

Spacer Length: 8.3 Å

 

Deuterated Crosslinkers氘代交聯劑產品:

產品名稱:BS2G-d4

BS2G-d4 deuterated crosslinker, Bis(Sulfosuccinimidyl) 2,2,4,4-glutarate-d4, is a water soluble and cell membrane impermeable crosslinking agent with 4 deuterium atoms to provide a 4 dal-ton shift by mass spectrometry analysis. Use BS2G-d4 crosslinking reagent in combination with the non-deuterated form of BS2G c1126-100mg or c1126-1gm for mass spectrometry studies.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 534.37

Spacer Length: 7.7 Å

Alternative Names: Glutaric acid-2,2,4,4-d4 bis (3-sulfo-N-hydroxysuccinimide ester) disodium salt

 

 

BS3-d4

BS3-d4 deuterated crosslinker, Bis(Sulfosuccinimidyl) 2,2,7,7-suberate-d4, is a water soluble and membrane impermeable crosslinking agent with 4 deuterium atoms to provide a 4 dalton shift by mass spectrometry. Use in combination with non-deuterated BS3 c1103-100mg or c1103-1gm for mass spectrometry studies.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)

Molecular Weight: 576.45

Spacer Length: 11.4 Å

Alternative Names: Suberic acid-2,2,7,7-d4 bis (3-sulfo-N-hydroxysuccinimide ester) disodium salt;

 

DSG-d4

DSG-d4 deuterated protein crosslinker (Bis[Succinimidyl] 2,2,4,4-glutarate-d4) is a cell mem-brane permeable crosslinking agent with 4 deuterium atoms to provide a 4 dalton shift by mass spectrometry analysis. Use the DSG-d4 heavy protein crosslinker in combination with the light, non-deuterated analog DSG (c1104).for mass spectrometry studies.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

 

Molecular Weight: 330.28

Spacer Length: 7.7Å

Alternative Names: Glutaric acid-2,2,4,4-d4 bis (N-hydroxysuccinimide ester);

 

DSS-d4

DSS-d4 deuterated crosslinker (Bis[Succinimidyl] 2,2,7,7-suberate-d4) is a cell membrane perme-able crosslinking agent with 4 deuterium atoms that provide a 4 dalton shift by mass spectrome-try analysis. Use DSS-d4 heavy crosslinker in combination with DSS, the light non-deuterated analog c1105-100mg or c1105-1gm, for mass spec studies.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 372.36

Spacer Length: 11.4 Å

Alternative Names: Suberic acid-2,2,7,7-d4 bis (N-hydroxysuccinimide ester);

 

DSP-d8

DSP-d8 deuterated protein crosslinker, Dithiobis(succinimidyl 2,2,3,3,6,6,7,7-propionate-d8), is a cell membrane permeable, homobifunctional protein crosslinker containing 8 deuterium atoms to provide an 8 dalton shift by mass spectrometry compared to non-deuterated DSP. DSP-d8 has amine-reactive NHS esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm. DSP-d8 contains a reducible disulfide bond (SS-bond) in the spacer arm. Use the DSP-d8 deuterated protein crosslinking reagent in combination with non-deuterated analog DSP for MS studies

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 412.46

Spacer Length: 12.0 Å

Alternative Names: Dithiobis(succinimidyl) propionate-d8; DSP-d8

 

Biotinylation Reagents生物素交聯試劑:

產品名稱:Biotin Hydrazide

Biotin Hydrazide (Biotin-Hz) is a carbohydrate reactive biotinylation reagent. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nucleic acids, and glycoprotiens. Typically, Biotin Hydrazide is used for coupling gly-coproteins through the carbohydrate by hydrazone formation.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 258.3

CAS #: 66640-86-6

Spacer Length: 15.7 Å

Alternative Name: (+)-Biotin Hydrazide

 

產品名稱:NHS-Biotin

NHS-Biotin (Succinimidyl Biotin; Succinimidobiotin) is a primary amine reactive biotinylation reagent. The NHS-Biotin molecule is cell membrane permeable and can be used to covalently label intracellular proteins.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 341.4

CAS #: 35013-72-0

Spacer Length: 13.5 Å

Alternative Names: Succinimidobiotin; Biotin-OSU; Biotin N-hydroxysuccinimide ester

 

產品名稱:NHS-SS-Biotin

NHS-SS-Biotin, Succinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate, is an amine-reactive biotinylation reagent that contains a reducible disulfide. NHS-SS-Biotin is cell membrane per-meable and has a long chain separating the biotin group from the amino-reactive NHS-ester (N-Hydroxysuccinimide ester). This product is often used to purify an antibody or other protein from a biotin specific affinity resin like immobilized streptavidin without exposing your protein of interest to denaturing conditions.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 504.7

CAS #: 142439-92-7

Spacer Length: 24.3 Å

Alternative Name: Biotin disulfide N-Hydroxysuccinimide ester

 

產品名稱:Sulfo-NHS-Biotin

Sulfo-NHS-Biotin (Sulfosuccinimidyl biotin) is a water soluble biotinylation reagent. It is amine reactive and has a spacer arm length of 13.5Å. The Sulfo-NHS-Biotin biotinylation reagent is ideal for biotinylating antibody or protein that can then be used for protein detection or immobi-lization. Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

 

Molecular Weight: 443.4

CAS #: 119616-92-5

Spacer Length: 13.5 Å

Alternative Names: Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt;

 

產品名稱:Sulfo-NHS-LC-Biotin

Sulfo-NHS-LC-Biotin, Sulfosuccinimidyl 6-(biotinamido) Hexanoate, is a long chain water solu-ble biotinylation reagent that is reactive toward primary amine groups. Similar to Sulfo-NHS-Biotin (b2100-100mg and b2100-1gm), Sulfo-NHS-LC-Biotin is designed to target cell surface proteins. The sodium sulfonate groups lend water solubility to Sulfo-NHS-LC-Biotin and prevent it from crossing the lipid bi-layer of the cell membrane.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

 

Molecular Weight: 556.6

CAS #: 128062-22-0

Spacer Length: 22.4 Å

Alternative Name: Biotinamidohexanoic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt

 

產品名稱:Sulfo-NHS-SS-Biotin

Sulfosuccinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate (Sulfo-NHS-SS-Biotin) is a cleava-ble, water-soluble, amino-reactive biotinylation reagent. This molecule is cell membrane imper-meable due to its sodium sulfonate group. Sulfo-NHS-SS-Biotin has a long chain spacer arm sep-arating the biotin group from the amino-reactive sulfo-NHS ester moity. It is possible to cleave the biotin group from the crosslinked target protein under reducing conditions, such as in the presence of BME, DTT or TCEP.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

 

Molecular Weight: 606.7

CAS #: 202057-28-1

Spacer Length: 24.3 Å

Alternative Name: Biotin disulfide N-Hydroxysulfosuccinimide ester

 

Other Modifications其他交聯劑產品:

產品名稱:HPG

HPG protein modification reagent (p-Hydroxyphenylglyoxal) reacts with arginine residues to give a large increase in absorbance at approximately 340 nm. The HPG is a better choice for ami-no acid side chain modification due to its increased water solubility over phenylglyoxal and im-proved oxidation resistance over p-nitrophenylglyoxal. Chemical Formula: C8H8O4

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

 

Molecular Weight: 168.2

CAS #: 24645-80-5

Alternative Names: p-Hydroxyphenylglyoxal monohydrate; 4-hydroxyphenylglyoxal;

 

產品名稱:SATA

SATA (N-Succinimidyl-S-Acetyl-Thioacetate) is a protein modification reagent used to convert primary amine groups into protected sulfhydryls (thiol; -SH). The sulfhydryl is readily made available for use in subsequent reactions after exposure to hydroxylamine.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

CAS #: 76931-93-6

Molecular Weight: 231.2

Alternative Names: S-Acetylthioglycolic acid N-hydroxysuccinimide ester

 

產品名稱:Sulfo-NHS Acetate

Sulfo-NHS-Acetate acylating agent (Sulfosuccinimidyl Acetate) is a water soluble. Sulfo-NHS-Acetate irreversibly reacts with primary amines, such as in lysine, at pH greater than 7 to yield the acylated form. Using Sulfo-NHS Acetate prevents polymerization when performing protein crosslinking reactions.

雙功能蛋白交聯劑和生物素交聯劑介紹(含結構式和英文介紹)
 

Molecular Weight: 259.17

CAS #: 152305-87-8

Alternative Names: 1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid

 

產品列表:

Sulfo-NHS    CAS #: 106627-54-7

BS3          CAS #: 82436-77-9

BS2G

BSG          CAS #: 79642-50-5

DSP          CAS #: 57757-57-0

DSS          CAS #: 68528-80-3

DTSSP        CAS #: 81069-02-5

EGS          CAS #: 70539-42-3

Sulfo-EGS    

DSSeb        CAS # 23024-29-5

BMPS         CAS #: 55750-62-4

EMCS         CAS #: 55750-63-5

GMBS         CAS #: 80307-12-6

LC-SPDP             

MBS          CAS #: 58626-38-3

PDPH           

SBA          CAS #: 42014-51-7     

SIA          CAS #: 39028-27-8

SMCC         CAS #: 64987-85-5

SMPB         CAS #: 79886-55-8

SMPH           

SPDP         CAS #: 68181-17-9

Sulfo-LC-SPDP    

Sulfo-MBS    

Sulfo-SANPAH CAS #: 102568-43-4

Sulfo-SMCC   CAS #: 92921-24-9

BS2G-d4

BS3-d4

DSG-d4

DSS-d4

DSP-d8

Biotin Hydrazide CAS #: 66640-86-6

NHS-Biotin       CAS #: 35013-72-0

NHS-SS-Biotin    CAS #: 142439-92-7

Sulfo-NHS-Biotin CAS #: 119616-92-5

Sulfo-NHS-LC-Biotin    CAS #: 128062-22-0

Sulfo-NHS-SS-Biotin    CAS #: 202057-28-1

HPG              CAS #: 24645-80-5

SATA             CAS #: 76931-93-6

Sulfo-NHS Acetate CAS #: 152305-87-8

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