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--sigma C1386 姜黃素(Curcumin)
  • --sigma C1386 姜黃素(Curcumin)
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貨物所在地:上海上海市

地: 楊浦區長陽路999號伊斯頓商務樓302-303室

更新時間:2024-10-07 21:00:07

瀏覽次數:628

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CAS Number: 458-37-7 Linear Formula: [HOC6H3(OCH3)CH=CHCO]2CH2 Molecular Weight: 368.38 Colour Index Number: 75300 Beilstein Registry Number: 2306965

Description

Biochem/physiol Actions A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Properties

biological source from Curcuma longa (Turmeric)
vapor density 13 (vs air)
assay ~70% (HPLC)
form powder
color orange
solubility ethanol: 10 mg/mL
  DMSO: >11 mg/mL
  0.5 M NaOH: then immediay dilute in PBSsoluble
Gene Information human ... APP(351), CYP1A2(1544)
storage temp. ?20°C

Safety

Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 2
RTECS MI5230000

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