玉研儀器基于十余年動物血壓測量經(jīng)驗，采用國際認(rèn)可先進(jìn)的非侵入式測量技術(shù)，自主研發(fā)專為大小鼠等實(shí)驗動物設(shè)計的無創(chuàng)血壓測量系統(tǒng)，無創(chuàng)準(zhǔn)確快速地測量動物的收縮壓、舒張壓、平均壓數(shù)據(jù)，結(jié)果與有創(chuàng)測量結(jié)果高度一致，數(shù)據(jù)穩(wěn)定，動物應(yīng)激反應(yīng)小，為藥物篩選及心血管疾病模型研究提供關(guān)鍵數(shù)據(jù)支持。

大鼠小鼠無創(chuàng)血壓測量儀介紹：

大小鼠血壓測量系統(tǒng)適合對大鼠小鼠進(jìn)行式的血壓測量，通過對鼠尾根部的實(shí)時檢測，精確測量出大鼠、小鼠的收縮壓、舒張壓、平均壓、心率。

美國IITC生命科學(xué)儀器公司成立于1973年，其血壓測量系統(tǒng)應(yīng)用于的生命科學(xué)研究領(lǐng)域，經(jīng)過不斷的改進(jìn)和拓展血壓測量系統(tǒng)和測痛產(chǎn)品系列，其產(chǎn)品已用于實(shí)驗室，也被數(shù)千篇國際論文所引用。

MRBP血壓測量系統(tǒng)能夠測量最少一只，可同時測量200只動物，是經(jīng)過實(shí)踐驗證的非常有效的手段和數(shù)據(jù)采集法，可以切實(shí)協(xié)助研究人員快速準(zhǔn)確的在比較低的推薦溫度下對動物進(jìn)行血壓測量。

大鼠小鼠無創(chuàng)血壓測量儀主要特點(diǎn)：

· 數(shù)百家實(shí)驗室使用，上千篇文獻(xiàn)支持；

· 真實(shí)反映動物血壓，與直測血壓有99%的相近；

· 直接測量SBP（收縮壓）、DBP（舒張壓）、HR（心率）同時出MBP（平均壓）；

· 專業(yè)的分析軟件滿足不同客戶的數(shù)據(jù)分析；

· 使用示波法和紅外感應(yīng)或血容量的測量方法，數(shù)據(jù)更加精確；

· 可根據(jù)需要，選擇多通道配置，同時測量多只大鼠或多只小鼠；

· 帶自動溫控保暖平臺，給動物維持一個穩(wěn)定舒適的測量環(huán)境；

· 配置靈活，自由搭配：大鼠小鼠通用型檢測平臺，可根據(jù)需要選購大鼠或小鼠測試適配器。

型號：MRBP

精確度高

· 實(shí)驗數(shù)據(jù)為數(shù)百篇已發(fā)表的同行評議論文采用；

· 范圍內(nèi)有幾百家實(shí)驗室引進(jìn)了血壓測量儀，這一覆蓋度是其他同類產(chǎn)品的。

多種模塊化配置，靈活方便

· MRBP有多種型號和價格供用戶選擇，能夠滿足各類實(shí)驗需要，符合不同用戶的預(yù)算標(biāo)準(zhǔn).所有的型號均配有一臺計算機(jī)和分析軟件，但是在可同時進(jìn)行測量的動物數(shù)量上有所差異；

· 主要分為：同時測量1只大鼠或小鼠，2只大鼠貨小鼠，3只大鼠或小鼠，4只大鼠或小鼠，....10只大鼠或小鼠同時測量。客戶可以根據(jù)自己的需要進(jìn)行選擇；

· 隨著研究的深入，您可以通過擴(kuò)展測量平臺，輕松的完成系統(tǒng)升級。

多通道血壓測量系統(tǒng)

易于使用

· MRBP的安裝過程非常簡單。硬件是參照人體工學(xué)理論設(shè)計的，目的是盡量方便用戶使用；

· 軟件就有很強(qiáng)的直觀性，因此您可以很快開始測量；

· 快捷的數(shù)據(jù)處理能力是實(shí)驗高效的保證

· MRBP能夠在嵌入數(shù)據(jù)中自動存儲和組織得到的數(shù)據(jù)

· 您可以根據(jù)需要提取相應(yīng)的數(shù)據(jù)報告，再保存為EXCEL文檔作深入分析。

實(shí)驗過程

· MRBP不僅能夠提供極精確的數(shù)據(jù)，在實(shí)驗流量很大的情況下還能保持高效率測量。這在大量測量表現(xiàn)性生物時時非常關(guān)鍵的；

· MRBP系統(tǒng)可以增加配置，同時測12只小鼠或大鼠；

· 大鼠小鼠通用一個平臺，只需要更換傳感器和鼠筒，就可以進(jìn)行大鼠小鼠的測量；

· 為了更大程度的提高實(shí)驗流量，你可以配備更多的大鼠、小鼠固定器，讓老鼠盡快調(diào)整到可以接受測量的狀態(tài)，為接下來的實(shí)驗作準(zhǔn)備；

· MRBP的可擴(kuò)展性和靈活性是同類產(chǎn)品的。

不同規(guī)格的老鼠固定筒

分析軟件

· MRBP分析軟件界面直觀，您可以很快開始測量；

· 測量過程中的所有信息都會以波形的形式體現(xiàn)在各個窗口，嵌入式數(shù)據(jù)庫能夠儲藏和組織所有的數(shù)據(jù)；

· Wizard報告可以生成數(shù)據(jù)報告，您可以根據(jù)需要提取相應(yīng)的數(shù)據(jù)，再保存為EXCEL文檔作深入分析；

· 軟件可免費(fèi)升級。

鼠傳感器

配合大小鼠血壓測量系統(tǒng)使用，有多種規(guī)格可供選擇：

每種規(guī)格對應(yīng)的大鼠、小鼠體重范圍如下：

價值

· MRBP能為您的投資帶來豐厚的回報；

· 綜合MRBP的所有性能，我們可以清楚的看到MRBP是用戶的良好選擇；

· 玉研儀器熱忱地歡迎您的來電來函！我們將根據(jù)您的需要，為您提供滿意的專業(yè)售前、售后服務(wù)，以及技術(shù)支持和產(chǎn)品培訓(xùn)。

大小鼠的部分參考文獻(xiàn)：

Geraniol improves endothelial function by inhibiting NOX-2 derived oxidative stress in high fat diet fed mice

X Wang, S Zhao, M Su, L Sun, S Zhang, D Wang… - Biochemical and …, 2016 - Elsevier

... HFD controls; n = 20) for 6 weeks. After 6 weeks, systolic blood pressure was measured using tail cuff plethysmography (IITC Life Science MRBP Blood Pressure System). The mice were deeply anaesthetized with sodium pentobarbital ...

Disruption of calpain reduces lipotoxicity-induced cardiac injury by preventing endoplasmic reticulum stress

S Li, L Zhang, R Ni, T Cao, D Zheng, S Xiong… - … et Biophysica Acta (BBA …, 2016 - Elsevier

... Animals were acclimated in the environment for 5–10 min after occlusion cuffs and pulse transducers (MRBP system, IITC Life Science, USA) were placed on the tail. The values of at least 10 readings for each mouse were used for blood pressure. 2.4. ...

Influence of P2X receptors on renal medullary circulation is not altered by angiotensin II pretreatment

M Kuczeriszka, L Dobrowolski, A Walkowska… - Pharmacological …, 2016 - Elsevier

... We confirmed that with this procedure systolic blood pressure (tail-cuff method, MRBP-3R, IITC Inc., Woodlａnd Hills, CA, USA) increased gradually to about 190 mmHg, compared to about 130 mmHg measured in untreated SD rats. ...

Protective Effects of At1-Receptor Blocker and Ca Antagonist Combination on Renal Function in Salt Loaded Spontaneously Hypertensive Rats/Протективни Ефекти …

K Gjorgjievska, D Zafirov, M Jurhar-Pavlova… - prilozi, 2015 -

... function tests. SBP was measured by a pletismografic method (IITC Life Science MRBP Blood Pressure System, California, USA) on the rats tail. Body weight was measured every second week of treatment. Renal functional ...

The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury

E Rübig, J Stypmann, P Van Slyke, DJ Dumont… - Scientific …, 2016 - ncbi.nlm.nih.gov

... Immediately before the first ultrasound examination, average blood pressure and heart rate were measured via tail cuff in each animal (5 measurements) using the mouse blood pressure system MRBP-M01 (IITC Life science, Woodlａnd Hills, CA, USA). ...

Changes in protein and gene expression of angiotensin II receptors (AT1 and AT2) in aorta of diabetic and hypertensive rats

R Romero-Nava, JE Rodriguez… - Clinical and …, 2016 - Taylor & Francis

... Systolic blood pressure (SBP) and heart rate were measured by a non-invasive blood pressure tail-cuff method (MRBP Blood Pressure system, IITC, Life Science, Woodlａnd Hills, CA)  ...

Low-dose Insulin Treatment Ameliorate Glucose Metabolism in Type 1 Diabetic Rats. J Diabetes Metab 7: 635. doi: 10.4172/2155-6156.1000 635 Page 2 of 8 …

AXH Ng, SH Ton, KA Kadir - 2016 -

... The blood pressure of rats were measured once every week using the MRBP Mouse and Rat Tail Cuff Method Blood Pressure System (IITC Life Sciences, USA). The tail cuff with pulse transducer was applied onto the tail of the rat placed in a plastic restrainer. ...

Benefício da Utiliza??o do Novo Alimento Funcional Salgante sem Sódio sobre os Níveis de Press?o Arterial em Animais Hipertensos

FSM Rodrigues, MA Yasuda, L de Paula… - Revista de Pesquisa …, 2015 - .br

... Os parametros foram aferidos através de método n?o invasivo (indireto) utilizando equipamento MRBP (Mouse Rat Blood Pressure- IITC Life Science) nos dias zero (sem tratamento com NaCl ou Salgante - pó de aspecto cristalino, branco e fino, solúvel em água, com odor ...

Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressureulcers

B Fromy, E Lingueglia, D Sigaudo-Roussel… - Nature medicine, 2012 -

... The experimental protocol was approved by the scientific and ethics committees of the University Claude Bernard Lyon 1, France (no. ... Blood pressure was monitored noninvasively throughout the experiment using a tail cuff system (IITC INC/Life Science Instruments). ..  《Nature Medicine》,五年影響因子高達(dá)27.887）

Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor

CRJ Kennedy, Y Zhang, S Brandon, Y Guan… - Nature medicine, 1999 -

... Mouse blood pressure was measured using an IITC Life Science Model 27 cuff pump with a Model 179 blood pressure analyzer. ...

Chronic β-adrenergic stimulation induces myocardial proinflammatory cytokine expression

DR Murray, SD Prabhu, B Chandrasekar - Circulation, 2000 - Am Heart Assoc

... System–Audie Murphy Division, San Antonio, Tex (DRM, BC), and the University of Louisville Health Sciences Center, Louisville ... 1 · d ?1 , n=8) or saline (n=7). After anesthesia, measures of body weight, blood pressure, and heart rate (tail cuff, IITC Life Science model 29 ...

Circulation 新的影響因子為15.202 (2013) ,該雜志 2011年在 CARDIAC & CARDIOVASCULAR SYSTEMS （心血管） 同類期刊中的影響因子幾位。