英文名稱 | Anti-TLR4 Polyclonal Antibody |
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宿主 | Rabbit |
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別名 | ARMD10;CD284;TLR-4;TOLL |
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應用 | WB |
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稀釋比例 | WB 1:500-2000. |
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交叉反應 | Human Mouse Rat |
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蛋白分子量 | 73kDa |
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Gene ID | 7099 |
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保存 | Store at -20°C. Avoid freeze / thaw cycles. |
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儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
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純化方法 | Affinity purification |
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亞型 | IgG |
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免疫原 | Recombinant protein of human TLR4 |
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性狀 | 液體 |
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Public Immunogen Range | Recombinant protein of human TLR4 |
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Subcellular Locations | Cytoplasm Cell membrane |
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Swiss Prot | O00206 |
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克隆類型 | Polyclonal Antibody |
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背景資料 | Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. |
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