目錄:北京索萊寶科技有限公司>>抗體>>Polyclonal Antibody>> K106458PAnti-MYC Polyclonal Antibody
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供貨周期:現(xiàn)貨 規(guī)格:50ul/100ul 貨號:K106458P 應(yīng)用領(lǐng)域:醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) 主要用途:WB IHC
>更新時間:2022-08-15 06:26:40瀏覽次數(shù):783評價
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供貨周期 | 現(xiàn)貨 | 規(guī)格 | 50ul/100ul |
---|---|---|---|
貨號 | K106458P | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)業(yè) |
主要用途 | WB IHC |
Anti-MYC Polyclonal Antibody
英文名稱 | Anti-MYC Polyclonal Antibody |
---|---|
宿主 | Rabbit |
別名 | BHLHE39;c-Myc;MRTL;MYCC |
應(yīng)用 | WB IHC |
稀釋比例 | WB 1:2000-5000.IHC 1:50-200. |
交叉反應(yīng) | Human Mouse Rat |
蛋白分子量 | 63kDa |
Gene ID | 4609 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
純化方法 | Affinity purification |
亞型 | IgG |
免疫原 | A synthetic peptide of human MYC |
性狀 | 液體 |
Public Immunogen Range | A synthetic peptide of human MYC |
Swiss Prot | P01106 |
Subcellular Locations | Nucleus Cytoplasm |
克隆類型 | Polyclonal Antibody |
背景資料 | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
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