ROCHE 11828681001- Annexin-V-FLUOS
參考價 | ¥ 5426 |
訂貨量 | ≥1 |
- 公司名稱 上海葉舟生物科技有限公司
- 品牌
- 型號 ROCHE 11828681001-
- 產地
- 廠商性質 經銷商
- 更新時間 2017/7/17 10:33:16
- 訪問次數 796
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產品名稱:Annexin-V-FLUOS
產品貨號:11828681001
產品包裝:500 µl 250 tests
產品價格:5426
產品應用:The analysis of phosphatidylserine on the outer leaflet of apoptotic cell membranes is performed using Annexin-V-FLUOS. Additionally, labeling with propidium iodide (PI) or with a cell surface marker can be used for differentiation from necrotic cells.
產品介紹:
Detection: can be directly detected in FACS analysis and immunochemistry without a secondary detection system.
Sample material:Cell lines and freshly isolated cells.
Specificity:Annexin-V binds in a calcium-dependent manner to negatively charged phospholipid surfaces, and shows high affinity for phosphatidylserine.
背景信息:In the early stages of apoptosis, changes occur on the cell surface (e.g., translocation of phosphatidylserine [PS] from the interior side of the plasma membrane to the outer leaflet). This secretion of phosphatidylserine is the ideal basis for Annexin-V, which binds to PS with high affinity. Annexin-V is a Ca2+-dependent phospholipid-binding protein with a high affinity for PS. Since necrotic cells also expose PS as a result of lost membrane integrity, apoptotic cells must be differentiated from these necrotic cells. The simultaneous application of a DNA stain, which is used for dye-exclusion testing, allows the discrimination of necrotic cells from the Annexin-V positively stained cell cluster.
組成:500 µl, ready-to-use solution, for 250 tests